Bloodwork Crisis (Earth-Prime)

"Feel them... millions of worlds waiting for your lifeblood. A gateway to the Multiverse."

- Ramsey Rosso

The Bloodwork Crisis was an event where Bloodwork was infecting everyone in the multiverse.

Aftermath
"So it looks like you'll be spending the rest of your human days as a regular criminal. Where you're going to rot until old age, just like everyone else."

- Kid Flash and Spartan to Rosso

Ramsey Rosso lost his powers and was cured of his HLH before being imprisoned for the rest of his life.