O Mother, Where Art Thou?

Synopsis
Lana reaches out to Lois and Clark when Kyle starts behaving strangely. Meanwhile, Jonathan opens up to Jordan. Lastly, Sarah storms out after accusing her mom of always covering for her dad.

Main Characters

 * Superman/Clark Kent (Kal-El)
 * Lois Lane
 * Sam Lane
 * Jordan Kent
 * Jonathan Kent
 * Lara Lor-Van (Lana Lang Cushing)
 * Sarah Cushing
 * Sarah Cushing

Villains

 * Subjekts
 * Morgan Edge (Tal-Rho)
 * Kyle Cushing
 * Emily Phan
 * Leslie Larr
 * Irma Sayres
 * Dabney Donovan
 * Jasper Townes
 * Dabney Donovan
 * Jasper Townes

Other Characters

 * DOD
 * Robins
 * Antony
 * DOD
 * Robins
 * Antony
 * DOD
 * Robins
 * Antony
 * DOD
 * Robins
 * Antony
 * Antony

Teams and Organizations

 * Edge EnerCorp
 * Subjekts
 * DOD
 * Defense Threat Reduction Agency
 * United States Army
 * Sequoia
 * Seek & Keep Thrift Store
 * Victoria May's Diner
 * Smallville Community Bank
 * Victoria May's Diner
 * Smallville Community Bank
 * Smallville Community Bank
 * Smallville Community Bank

Species

 * Kryptonians
 * Humans
 * Metahumans
 * Human-Kryptonian Hybrids
 * A.I.

Objects

 * Superman Suit
 * Tal-Rho's Suit
 * X-Kryptonite
 * Clark Kent's Glasses
 * Holograms
 * Sunstone Crystal
 * Eradicator
 * Green Kryptonite
 * Power-Dampening Cuffs
 * Kent Farm Truck
 * Kryptonian Skinsuits
 * Kryptonian Skinsuits
 * Kryptonian Skinsuits
 * Kryptonian Skinsuits

Locations

 * Earth-Prime
 * Earth
 * United States of America
 * Kansas
 * Rice County
 * Smallville
 * Cushing Residence
 * Kent Farm
 * Kent House
 * Kent Barn
 * Main Street
 * Sequoia
 * DOD Smallville Camp
 * Seek & Keep Thrift Store
 * Victoria May's Diner
 * Smallville Community Bank
 * Arctic
 * Fortress of Solitude
 * Arctic
 * Fortress of Solitude
 * Arctic
 * Fortress of Solitude
 * Arctic
 * Fortress of Solitude

Trivia

 * The episode title is a play to the 2000 film "O Brother, Where Art Thou?". Coincidentally, an episode of  also referenced the film.